Discussed in this episode: A new paper finds that SARS-COV2 infects a type of immune cell the in the lungs called interstitial macrophages, helping to explain the cascade of inflammation, lung damage, and scarring seen in severe COVID-19. The virus enters those cells using a receptor (CD209) different from the ACE2 receptor targeted by current … Continued

Discussed in this episode: A newly-published study in Nature Neuroscience points to a likely mechanism by which Long Covid produces neurological symptoms like brain fog: disruption of the blood-brain barrier Because of fundraising at KPFA, we’ll only be taking questions via email for the next week (the station needs its phone lines free for people … Continued

Discussed in this episode: A new article in the journal Cell finds Long Covid associated with reduced levels of serotonin circulating in the bloodstream. (The authors’ explanation: the persistent presence of the virus, and/or its fragments, causes the body to crank out more type I interferons. The interferons cause  inflammation in the gut that reduces uptake … Continued


House Speaker Vote; Plus, New Report Shows Impact of Covid-19 on K-12 Education

0:08 — John Nichols is National Affairs Correspondent for the Nation  0:33 — Robin Lake, director of the Center on Reinventing Public Education at Arizona State University.  Chelsea Waite, senior researcher at the Center on Reinventing Public Education. Morgan Polikoff, is an Associate Professor at the USC Rossier School of Education  

Discussed in this episode: COVID hospitalizations continue to trend up, nearly doubling rates from mid-summer. (That’s a large increase from a low baseline: in most of the country, hospitalization rates are still what the CDC considers “low.”) A new observational study using patient data from Stockholm suggests the percent of COVID cases that result in … Continued

Discussed in this episode: A new paper in Science Translational Medicine draws results from animal experiments, human samples, and human autopsies to suggest a mechanism for some cases of Long Covid: the virus binds to a protein on our cells’ mitochondria and can enduringly alter their function. Podcast music credit:  Now Son by Podington Bear, licensed under a Attribution-NonCommercial 3.0 … Continued

Discussed in this episode: New research published in Nature examined if people who got infected without showing symptoms had something in common genetically. They did: a mutation on the  HLA-B (that’s short for Human Leukocyte Antigen) gene. In the laboratory, T-cell samples collected from those people *before* infection reacted strongly to SARS-COV2, suggesting the mutation helps … Continued