Against the Grain

Manipulating Alzheimer’s Research

Billions of dollars have been spent on Alzheimer’s research over many decades, yet no effective treatment exists. Investigative journalist Charles Piller has revealed one reason for the impasse: pivotal scientific research into Alzheimer’s disease — affirming the hypothesis that it’s caused by sticky amyloid plaques in the brain — was based on manipulated images.

Resources:

Charles Piller, Doctored: Fraud, Arrogance, and Tragedy in the Quest to Cure Alzheimer’s One Signal, 2025